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中文
这个靶向构建是通过将FRT-NEO-FRT-IRES-CRE的 cassette插入基因的终止密码子和polyA位点之间，在胚胎干细胞中通过同源重组生成的。这种方法使得产生了能正确靶向小鼠的后代。将这些带有目标 cassette 的小鼠与FlpO剔除小鼠杂交后，就去除了选择性 cassette(来源：J:238329)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
