这些转基因小鼠表达的人类胎盘源性生长因子1(TDGF1,又称Cripto-1或CR-1),是通过乳清酸蛋白基因(Wap)的启动子调控的。转基因中包含Wap启动子,随后是人类TDGF1 cDNA的编码序列,两侧各220bp的5'非翻译区和110bp的3'非翻译区,以及牛生长激素的polyadenylation信号。(来源:J:99942)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
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Year
IF
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