将一个经过密码子优化的IRES-MercreMer基因(MercreMer:连接了两个改造过的雌激素受体配体结合域,一端是cre重组酶,另一端是Frt-flanked Neo标记选择子)与Kit基因的3'非翻译区(在终止密码子后20bp位置)通过同源重组插入胚胎干细胞中。(来源:J:233387)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
BALB/c
Targeted
插入
--
1
27
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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