这些靶向载体是通过RP23-230B21 BAC克隆构建的。载体中整合了一种带有polyA序列和FRT标记的CreERTM融合蛋白,以及一个FRT引导的PGK-Neo cassette,它位于Lefty1基因的起始exon位置。通过FLPe介导的重组,PGK-Neo cassette被剔除了,留下一个单独的FRT位点。(来源:J:222398)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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