通过Cre介导的重组,目标敲除-先期准备-父本基因型Esys1tm1Tmss去除了3到7号的neo和creitical外显子,导致在基因的第2 intron内插入了FRT接点、splice接受器、lacZ序列以及polyadenylation序列,最后跟着一个loxP位点。(来源:J:236096)
Basic Information
STOCK 129/Sv and C57BL/6J and SJL
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count