Cre介导的重组已经删除了一段从exon 2上游335bp的DNA序列,这个序列包含了整个编码区域,延伸到exon的终止密码子下游550bp的位置,留下了一个loxP位点。原本目标等位基因Grem1tm1Ecan(J:126375)的exon 2剩余部分被删除了66bp。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129 x C57BL/6)F1
Targeted
插入,基因内删除
--
1
2
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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