靶向载体包含一个由loxP切割位点引导的FLAG-myc-STOP插件,位于EGFP序列之前,所有这些都与内源性终止子同框插入。在Cre重组酶作用前,观察到FLAG/myc标记的RAI1的表达模式与内源基因一致,未报告EGFP的表达。(来源:J:237687)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S1/Sv
Targeted
插入
--
1
5
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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