删除父本Snap29tm1a(EUCOMM)Wtsi基因的Flp剪接会去除lacZ/neo元件,留下一个带有loxP标记的至关重要外显子2。欲了解针对此类IKMC等基因的其他靶向策略,请参阅http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml(来源:J:236759)。
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count