根据国际敲除小鼠联盟提供的等位分子图像,这个基因有loxP序列环绕着6号和7号外显子,插入在5号和6号外显子之间的内含子中有一个FRT位点,一个 engrailed 2 的剪接接受序列,一个EGFP表达元件以及cre/ERT2驱动的序列,最后是Rox标记的 puromycin抗性基因簇。(来源:J:155845)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N
Targeted
插入
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1
1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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