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中文
使用了一种包含S1991A、Y1292F、S1312A和Y1472F氨基酸替换突变，以及一个-loxP位点周围带有NEO cassette的靶向载体，目标是打断第12号外显子。通过Cre介导的重组，去除了含有的floxed neo cassette(来源：J:235504)。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
