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中文
转基因中包含了mouse actin, alpha 2, 平滑肌，主动脉（Acta2）基因的启动子区域，包括1074bp的5'上游序列、转录起始点、48bp的首外显子、约2.5kb的首内含子以及15bp的exon 2，驱动表达人类醛基酮还原酶家族1成员B（又称醛糖还原酶）。转基因小鼠在血管和平滑肌细胞，以及视网膜的锥形 bipolar细胞中特异性表达AKR1B1。（来源：J:43053, J:195671）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
