转基因中包含了mouse actin, alpha 2, 平滑肌,主动脉(Acta2)基因的启动子区域,包括5'端1074bp的上游序列、转录起始点、48bp的首外显子、约2.5kb的首内含子以及15bp的exon 2,驱动绿色荧光蛋白(GFP)的表达。转基因小鼠在血管和平滑肌非血管细胞中特异性表达GFP。(来源:J:43053, J:191415)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
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7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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