这个靶向构建包含一个四环素响应元件(TRE;tetO)-loxP-Stop-loxP-Optopatch2。Optopatch2是一个双顺式构建,同时表达QuasAr2-dark mOrange2(一种增强的Archaeoglobus thermophilus的光感受器-3,Arch的基质)和CheRiff-EGFP(一种对蓝移光激活有敏感性的光遗传学效应器),两者由猪细小病毒-1(P2A)肽分隔。来源:(J:101977)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(129S6/SvEvTac x C57BL/6NCrl)F1
Targeted
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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