这个靶向构建包含一个四环素响应元件(TRE;tetO)-loxP-Stop-loxP-Optopatch2。Optopatch2是一个双顺式构建,同时表达QuasAr2-dark mOrange2(一种增强的Archaeoglobus thermophilus的光感受器-3,Arch的基质)和CheRiff-EGFP(一种对蓝移光激活有敏感性的光遗传学效应器),两者由猪细小病毒-1(P2A)肽分隔。来源:(J:101977)
Basic Information
(129S6/SvEvTac x C57BL/6NCrl)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count