这个转基因是通过设计的,包含一个突变的人类KLF6基因,由胶原I型α2(Col1a2)驱动的promoter驱动。KLF6的替代剪接异构体-splice变异型1(SV1)缺失了DNA结合区域。(来源:J:235492)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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