一种包含T2A病毒2A多肽、iCre重组酶序列、T2A病毒2A多肽、来源于昆虫Thosea asigna病毒2A的多顺反子元件以及FRT位点周边的NEO cassette的靶向载体,被插入到Trpm2基因的终止密码子上游。生成的转基因动物与表达FLPeR重组酶(Gt(ROSA)26Sor)的雌性杂交,以去除FRT位点周边的NEO cassette(来源:J:235274)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129P2/OlaHsd)F1
Targeted
插入
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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