设计了一个靶向载体,用于将带有FLAG标签的mCherry荧光蛋白和Cre重组酶序列,通过两种不同的病毒2A寡聚肽(来自猪teschovirus-1的P2A和Insect Thosea asigna病毒的T2A)间隔插入马凡氏肌强直性营养不良相关基因家族蛋白B(简称v-maf)的编码序列中。载体末端包含3'位置的neomycin抗性基因(neo) cassette,随后通过与FLP1表达小鼠杂交去除neo cassette。来源:(J:101977)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N
Targeted
插入
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1
5
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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