Kdm4b^{tm1c(EUCOMM)Wtsi}

The L1L2_gt0 cassette was inserted at position 56662423 of Chromosome 17 upstream of the critical exon 5 (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon(s) at position 56663316. A "conditional ready" (floxed) allele was created by flp recombinase expression in mice, deleting the lacZ sequence and neomycin selection cassette. The critical exon 5 remains flanked by loxP sites. (J:234086)