这个靶向构建插入了a基因座,包含CAG启动子驱动的,带有Neomycin抗性基因簇的失活Neomycin抗性 cassette,以及5'和3'端由H序列标记的Mirc20微小RNA簇,以及由FRT序列引导的Neomycin抗性 cassette。通过Flp介导的重组,去除了FRT标记的Neomycin抗性元件。(来源:J:233994)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
Targeted
插入
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--
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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