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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
转基因模型
Tg(CMV-TLR10)5m3Tapp
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基础信息
表型特征
文献报道
转基因构建是由纯化并剪接过的CMV-FLAG-TLR10dsDNA(带有N端FLAG标签的人类TLR10)通过CMV(巨细胞病毒)启动子驱动产生的。转录基因在脾脏、肝脏和血液白细胞中通过 Western blot 方法检测表达。(来源:J:234393)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
5790660
C57BL/6NHsd
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Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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