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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
转基因模型
Tg(Foxp3-HBEGF/EGFP)1Doi
Alias:
Foxp3-DTR
Foxp3
DTR
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基础信息
表型特征
文献报道
包含Foxp3的BAC通过插入人类肝素结合表皮生长因子样生长因子(HBEGF或DTR,链球菌毒素受体)序列,该序列与增强绿色荧光蛋白(EGFP)连接,并在Foxp3开放阅读框的起始和第二个密码子之间插入了终止密码子,进行了修改。(来源:J:153752)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
5789576
NOD/ShiLtJ
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插入
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1
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7
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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