包含Foxp3的BAC通过插入人类肝素结合表皮生长因子样生长因子(HBEGF或DTR,链球菌毒素受体)序列,该序列与增强绿色荧光蛋白(EGFP)连接,并在Foxp3开放阅读框的起始和第二个密码子之间插入了终止密码子,进行了修改。(来源:J:153752)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
NOD/ShiLtJ
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插入
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1
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7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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