ENU-induced T to C transition at base pair 13,696,794 (v38) on chromosome 13, or base pair 106,456 in the GenBank genomic region NC_000079 for the Lyst gene. The effect of the mutation at the cDNA and protein level have not examined, but the mutation is predicted to result in skipping of the 179-nucleotide exon 30 (out of 53 total exons), resulting in an in-frame deletion of 59 amino acids after amino acid 2,643 of the protein. (J:234242)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Chemically induced
单点
隐性
1
2
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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