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中文
在最后一个外显子(24)的STOP密码子后面插入了靶向构建，包括一个loxP位点、IRE序列、lacZ报告基因、氨苄青霉素抗性基因和另一个loxP位点。第22外显子通过核苷酸替换改造，实现了第931位由Alanine替换为Aspartic acid(即D931A)的氨基酸改变。随后，Cre介导的重组去除了报告/选择元件。(来源：J:228659)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
