靶向载体包含一个loxP序列,后面跟着一个由FRT引导的诺卡因 cassette,位于J alpha 18(J alpha 281)基因段上游,接着是一个下游的loxP位点。通过Cre介导的重组,去除了J alpha 18段和neo cassette。(J:232957)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count