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中文
在exon 2的上游插入了一个loxP位点。下游的exon 3之后插入了一个FRT标记的诺卡因抗性元件，带有3'的loxP位点。通过Flp介导的重组移除了选择性元件。随后，Cre介导的重组去除了exons 2和3。 Western blot分析证实了在小鼠胚胎成纤维细胞中没有蛋白表达。(来源：J:232686)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
