这个基因的第二个也是最后一个外显子被敲除了,然后在3' UTR位置插入了IRES-mVenus。通过Cre介导的重组,这个外显子被移除了。西部印迹分析证实了大脑皮层中没有检测到蛋白质(来源:J:232548)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac x C57BL/6J
Targeted
插入,基因内删除
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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