将带有5'端病毒2A多肽(如T2A)的哺乳动物优化的噬菌体D6特异性重组酶基因(dreo)替换掉2号外显子的终止密码子和3'端41bp的UTR,但不改变编码序列。通过phiC31介导的重组,移除了重组酶基因下游插入的诺卡因抗性元件。(来源:J:232241)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129S6/SvEvTac x C57BL/6NCrl)F1
Targeted
插入
--
1
1
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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