在15号染色体的v38位点,由ENU诱导的A到C的转换,对应于GenBank序列NC_000081中的第6,839个碱基,或者说是NM_009008 mRNA序列的第78,565,945位,这个变异导致了精氨酸(Residue 332)被替换为异亮氨酸(Aspartic Acid to Alanine,D65A)。(来源:J:231801)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Chemically induced
单点
半显性
1
3
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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