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中文
设计了一条单个CRISPR导向RNA，目标定位在转膜区域之前的外显子2编码序列。通过将引导RNA和Cas9 mRNA注入到初级卵母细胞和细胞质中，产生了这种等位基因。选择了一个带有2个碱基插入（在第16个密码子后插入GT）的突变型，它会破坏ORF。预计这将产生一个缺少转膜区的截短蛋白。(来源：J:229305)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
