这个转基因包含了鼠神经特异性烯醇酶(Eno2)的启动子(包括调节序列:exon 1、内含子1和2号exon的6bp),它指导表达人类solute carrier family 29(核苷酸转运体)的一员,即SLC29A1或ENT1的cDNA,后面跟着一个polyA信号。SLC29A1的起始密码子与2号exon在同一条线上。表达在大脑皮层、纹状体、海马和小脑中。骨骼肌、心脏、肝脏、肾脏和肺的RNA样本中未检测到转基因的表达。(来源:J:231362)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
CD-1
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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