在microRNA序列上游插入了一个带有5' loxP位点的FRT引导的诺卡因抗性基因座,随后在microRNA序列下游插入了另一个loxP位点。通过Flp介导的重组去除了选择性基因座,而Cre介导的重组则剔除了被-loxP标记的microRNA序列。(来源:J:224629)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6J
Targeted
插入,基因内删除
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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