在exon 1的起始密码子上游插入了一个loxP位点。在起始密码子下游插入了一个串联亲和纯化(TAP)标签。下游插入了一个3'有loxP位点的FRT引导的诺卡因抗性基因座。通过Flp介导的重组,移除了选择性基因座,使得exon 1区域可被同源重组剪接掉。(来源:J:231214)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Targeted
插入
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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