大部分exon 1被替换了抗氨苄青霉素抗性基因 cassette。 Western blot结果显示,小鼠胚胎成纤维细胞中没有蛋白表达(来源:198791)
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Most of exon 1 was replaced with a neomycin resistance cassette. Western blot analysis confirmed the absence of protein expression in mouse embryonic fibroblasts. (J:198791)