Tomm22^em1(IMPC)J

This allele from project Tomm22-7567J-M3164 was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences CCTGGCCCTTCCGTGCCGCG, CGTGGACGCCGCGAGCCGAG, GTGGTTGGTCTTCTGCAGAA and CGGGTGCTGTCAAAGGACAG, which resulted in a 345 bp deletion spanning exon 2 beginning at Chromosome 15 positive strand position 79,671,092 bp, GCACGGAAGGGCCAGGCCCG, and ending after GAGTGTGGTTGGTCTTCTGC at 79,671,436 bp (GRCm38/mm10). This mutation deletes exon 2 and 225 bp of flanking intronic sequence including the splice acceptor and donor, and is predicted to cause a change of amino acid sequence after residue 39 and early truncation 22 amino acids later. (J:188991)