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中文
Exon 7被修改，插入了两个碱基突变(CT变为GG)，导致第260位氨基酸由Alanine替换为Glutamic Acid(艾尔氨酸替换为谷氨酸，E260A)。末端加入了C-terminal的血小板会聚素(HA)表位(YPYDVPDY)。同时，将IRES、MAPT(tau)和GFP报告基因融合插入了3' UTR。通过Flp介导的重组，去除了下游报告基因融合后插入的FRT引导的诺卡因抗性基因 cassette。来源：(J:229180)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
