在第二外显子上游插入了一个loxP位点,紧接着是富含AU的元件(ARE)。在第二外显子下游,插入了一个FRT引导的诺卡因抗性 cassette,内含flp重组酶基因,且带有3'的loxP位点。通过flp介导的重组,去除了选择性 cassette。(来源:J:226968)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
插入
--
1
3
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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