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中文
在exon 10上游插入了敲除型新霉素抗性基因座。exon 11被替换为删除了TG序列的改良版本。这种突变模拟了纳佐斯病患者发现的突变，导致exon 12处产生早停密码子。通过Flp介导的重组，去除了选择性基因座。RT-PCR证实了转录本表达量的降低。（来源：J:222025）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
