这个来自TCPR0258项目的等位基因是在表型基因组学中心通过向细胞中注入Cas9核酸酶和带有spacer序列GTGTATACTACCGTGCACCA的指导RNA产生的。这导致X染色体上一个7个碱基对的缺失,位置在161875339到161875345(GRCm38建库)。(来源:J:165963)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NCrl
Endonuclease-mediated
插入,基因内删除
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1
6
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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