这个等位基因是由TCPR0372项目在表观基因组学中心通过向染色体4的39,421,873至39,437,193位插入insCT(GRCm38建库)产生的,通过注入Cas9 mRNA和两条带有特定 Spacer序列(ATGCAAGCATACTATTACAC和AATTTGGGCTCTTTTAGGCC)的指导RNA实现。这个变异导致了1,533个碱基的缺失。 (来源:J:165963)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NCrl
Endonuclease-mediated
基因内删除
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1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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