Bcas1^em1(IMPC)Tcp

This allele produced from project TCPR0256 at The Centre for Phenogenomics by injecting Cas9 mRNA and one guide RNA with the spacer sequence GGTGCCAATGGGCCGGTGGC. This resulted in an insertion of 1 bp (A on the -1 strand) at Chr2:170406531 (GRCm38) in exon 4 (ENSMUSE00001221352). This mutation is predicted to cause a frameshift with amino acid changes after residue 169 and early truncation 6 amino acids later (p.T170Nfs*8). (J:165963)