Ano6^em3(IMPC)Tcp

This allele produced from project TCPR0236 at The Centre for Phenogenomics by injecting Cas9 mRNA and one guide RNA with the spacer sequence GGATCGGGTCTGTCCCGTTG. This resulted in an indel comprised of a 3-bp deletion from Chr15:95948364 to 95948366 (GRCm38) and a 2-bp insertion of AC into exon 13 (ENSMUSE00000275040) (GRCm38). This mutation is predicted to cause a frameshift with amino acid changes after residue 493 and early truncation 10 amino acids later (p.N494Kfs*10). (J:165963)