在microRNA序列的上游插入了一个loxP位点和F3引导的puromycin抗性元件,随后在该序列的下游插入了另一个loxP位点和一个FRT引导的neomycin抗性元件。通过Flp介导的重组,选择性元件被去除,留下了microRNA序列的loxP标记。来源:(J:221990)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6N
Targeted
插入
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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