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中文
在P8R基因的第1外显子插入了CCG>CGG的突变，通过同源重组在1号内含子中插入了floxed neo cassette。随后，通过Cre介导的重组移除了neo cassette。在纯合小鼠的脑和脊髓中，蛋白质水平相较于对照野生型减少了大约50-60%（来源：J:220605）。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
