一段8.5千碱基的人类野生型tau cDNA启动子,包含了上游调控区域和转录起始位点,能驱动前额叶神经元中tau蛋白的表达。 Western blot实验确认了在大脑中的表达,并且随着年龄的增长,tau蛋白的磷酸化水平升高。(来源:172762)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
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1
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3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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