在经同源重组,通过FRT序列插入了包含splice接受器、β-半乳糖苷酶、neo和polyA序列,以及在3号外显子上游的loxP位点,同时在3号外显子下游也插入了loxP位点的构建。这个靶向载体(设计编号39122)来自EUCOMM库。通过Flp介导的重组,移除了β-半乳糖苷酶和neo元件。(来源:J:219976)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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