在第六个内含子插入了一个loxP位点和一个FRT引导的pgk-neo插入片段,且该片段以相反方向存在。接着在第七个内含子插入了一个loxP位点。通过Flp介导的重组,neo cassette被移除,导致第七个外显子被标记为可翻转。(来源:J:219506)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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