通过Cre介导的父本Cracr2atm1(KOMP)Vlcg等位基因的去除,去除了新霉素选择标记基因,保留了插入的lacZ报告序列,且可能移除了关键的外显子。欲了解针对此类IKMC等位基因的其他靶向策略,请访问http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml(来源:J:204739)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NTac
Targeted
插入,基因内删除
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1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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