Exon 2被替换了抗氨苄青霉素抗性基因 cassette。对肝脏蛋白的 Western blot 检测显示,纯合突变小鼠相较于对照组,编码蛋白的表达缺失。(来源:J:223365)
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Exon 2 was replaced by a neomycin resistance cassette. Western blot of liver proteins showed a lack of encoded protein expression in homozygous mutant mice compared with control mice. (J:223365)