在第2外显子上游插入了FRT引导的neo cassette和一个loxP位点,通过同源重组,又在第3外显子下游插入了loxP位点。通过Flp介导的重组,neo cassette被移除,使得第2和3外显子被标记为可翻转(Floxed)。(来源:J:163763)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count