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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Ccdc80
tm1Ppal
Alias:
cl2/ccdc80
-
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基础信息
表型特征
文献报道
通过同源重组,一个包括1号外显子和大部分2号外显子(包括起始翻译位点)的基因区域被替换了新插入的neo cassette。RT-PCR结果显示,纯合突变小鼠甲状腺、脾、卵巢、肝脏和肾脏的组织中没有RNA表达(来源:J:217742)。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
5706809
Not Specified
Targeted
插入,基因内删除
--
1
--
1
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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