通过同源重组,研究人员在位点中插入了一个包含CAG启动子、LoxP位点、FRT标记的neo cassette、终止子、另一个LoxP位点、Foxn1 cDNA、IRES和GFP基因的构建。随后,Flp介导的重组去除了neo cassette。(来源:J:217716)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
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--
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4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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